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    Ly6g6d lymphocyte antigen 6 family member G6D [ Rattus norvegicus (Norway rat) ]

    Gene ID: 415062, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ly6g6dprovided by RGD
    Official Full Name
    lymphocyte antigen 6 family member G6Dprovided by RGD
    Primary source
    RGD:1303064
    See related
    EnsemblRapid:ENSRNOG00000027225 AllianceGenome:RGD:1303064
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    G6d; Ng25; Ly6-D
    Summary
    Predicted to enable acetylcholine receptor inhibitor activity and identical protein binding activity. Predicted to be involved in acetylcholine receptor signaling pathway. Predicted to be located in plasma membrane and synapse. Predicted to be part of protein-containing complex. Predicted to colocalize with external side of plasma membrane. Orthologous to human LY6G6D (lymphocyte antigen 6 family member G6D). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 12.2), Lung (RPKM 5.9) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ly6g6d in Genome Data Viewer
    Location:
    20p12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (3746630..3757036)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (3741973..3752378)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (5061849..5064768, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 16A, phospholipase Neighboring gene ribosomal protein S25, pseudogene 2 Neighboring gene lymphocyte antigen 6 family member G6F Neighboring gene lymphocyte antigen 6 family member G6E Neighboring gene lymphocyte antigen 6 family member G6C Neighboring gene megakaryocyte and platelet inhibitory receptor G6b

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables acetylcholine receptor inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables acetylcholine receptor inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in acetylcholine receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within acetylcholine receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lymphocyte antigen 6 complex locus protein G6d
    Names
    lymphocyte antigen 6 complex G6D
    lymphocyte antigen 6 complex, locus G6D

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001970.2NP_001001970.1  lymphocyte antigen 6 complex locus protein G6d isoform 1 precursor

      See identical proteins and their annotated locations for NP_001001970.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/Swiss-Prot
      Q6MG58
      UniProtKB/TrEMBL
      A0A1L6ZA25, A0A1L6ZA45
      Related
      ENSRNOP00000001120.3, ENSRNOT00000001120.5
    2. NM_001412147.1NP_001399076.1  lymphocyte antigen 6 complex locus protein G6d isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A0A1L6ZA25, A6KTS6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      3746630..3757036
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)