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    Iqca1l IQ motif containing with AAA domain 1 like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499971, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Iqca1lprovided by RGD
    Official Full Name
    IQ motif containing with AAA domain 1 likeprovided by RGD
    Primary source
    RGD:1564789
    See related
    EnsemblRapid:ENSRNOG00000011092 AllianceGenome:RGD:1564789
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Iqca1p1
    Summary
    Predicted to enable ATP binding activity and ATP hydrolysis activity. Orthologous to human IQCA1L (IQ motif containing with AAA domain 1 like). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Restricted expression toward (RPKM 24.7) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Iqca1l in Genome Data Viewer
    Location:
    4q11
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (11509121..11520765)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (10616677..10628300)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (7144674..7157106)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene chondroitin polymerizing factor 2 Neighboring gene microRNA 671 Neighboring gene ATP binding cassette subfamily F member 2 Neighboring gene ankyrin repeat and SOCS box-containing 10 Neighboring gene gastrulation brain homeobox 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    IQ and AAA domain-containing protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024317.2 → NP_001019488.2  IQ and AAA domain-containing protein 1-like

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/Swiss-Prot
      Q6AXQ7
      UniProtKB/TrEMBL
      A0A0A6YYL9
      Related
      ENSRNOP00000014998.6, ENSRNOT00000014998.7
      Conserved Domains (2) summary
      COG0464
      Location:563 → 738
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
      pfam00004
      Location:565 → 698
      AAA; ATPase family associated with various cellular activities (AAA)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      11509121..11520765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008762655.4 → XP_008760877.1  IQ and AAA domain-containing protein 1-like isoform X1

      UniProtKB/Swiss-Prot
      Q6AXQ7
      Conserved Domains (2) summary
      COG0464
      Location:432 → 607
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
      pfam00004
      Location:434 → 567
      AAA; ATPase family associated with various cellular activities (AAA)

    2. XM_017592773.3 → XP_017448262.1  IQ and AAA domain-containing protein 1-like isoform X2

      UniProtKB/Swiss-Prot
      Q6AXQ7
      Conserved Domains (2) summary
      COG0464
      Location:406 → 581
      SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
      pfam00004
      Location:408 → 541
      AAA; ATPase family associated with various cellular activities (AAA)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AXQ7.2 GenPept UniProtKB/Swiss-Prot:Q6AXQ7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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