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    Urb2 URB2 ribosome biogenesis homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292087, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Urb2provided by RGD
    Official Full Name
    URB2 ribosome biogenesis homologprovided by RGD
    Primary source
    RGD:1307980
    See related
    EnsemblRapid:ENSRNOG00000026853 AllianceGenome:RGD:1307980
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307980
    Summary
    Predicted to be involved in ribosome biogenesis. Predicted to be located in aggresome and midbody. Predicted to be active in nucleolus. Orthologous to human URB2 (URB2 ribosome biogenesis homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 59.7), Thymus (RPKM 42.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Urb2 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (68908466..68934058)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (52011019..52036607)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (56802843..56827017)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene nucleoporin 133 Neighboring gene uncharacterized LOC134483405 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene ATP binding cassette subfamily B member 10 Neighboring gene TATA-box binding protein associated factor 5 like 1 Neighboring gene eukaryotic translation initiation factor 4E, pseudogene 8 Neighboring gene large ribosomal subunit protein uL24-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. From midbody protein-protein interaction network construction to novel regulators in cytokinesis. Chen TC, et al. J Proteome Res, 2009 Nov. PMID 19799413
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in ribosome biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in aggresome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in aggresome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    unhealthy ribosome biogenesis protein 2 homolog
    Names
    URB2 ribosome biogenesis 2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135708.4 → NP_001129180.1  unhealthy ribosome biogenesis protein 2 homolog

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      D4AAN0
      Conserved Domains (1) summary
      pfam10441
      Location:1322 → 1517
      Urb2; Urb2/Npa2 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      68908466..68934058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277955.1 → XP_063134025.1  unhealthy ribosome biogenesis protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      D4AAN0

    2. XM_039097655.2 → XP_038953583.1  unhealthy ribosome biogenesis protein 2 homolog isoform X1

      UniProtKB/TrEMBL
      D4AAN0
      Related
      ENSRNOP00000029895.6, ENSRNOT00000036042.6
      Conserved Domains (1) summary
      pfam10441
      Location:1322 → 1517
      Urb2; Urb2/Npa2 family

    RNA

    1. XR_005496645.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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