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    Calhm5 calcium homeostasis modulator family member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294431, updated on 4-Jan-2025

    Summary

    Official Symbol
    Calhm5provided by RGD
    Official Full Name
    calcium homeostasis modulator family member 5provided by RGD
    Primary source
    RGD:1310405
    See related
    EnsemblRapid:ENSRNOG00000000825 AllianceGenome:RGD:1310405
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam26e; RGD1310405
    Summary
    Predicted to enable monoatomic cation channel activity. Predicted to be involved in ATP export and monoatomic cation transmembrane transport. Predicted to be active in plasma membrane. Orthologous to human CALHM5 (calcium homeostasis modulator family member 5). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Muscle (RPKM 66.4), Heart (RPKM 66.0) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Calhm5 in Genome Data Viewer
    Location:
    20q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (26609400..26615478, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (26066270..26072348, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (27651817..27673817, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene RWD domain containing 1 Neighboring gene trafficking protein particle complex subunit 3L Neighboring gene calcium homeostasis modulator family member 4 Neighboring gene calcium homeostasis modulator family member 6 Neighboring gene dermatan sulfate epimerase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables monoatomic cation channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in ATP export IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    calcium homeostasis modulator protein 5
    Names
    family with sequence similarity 26, member E
    protein FAM26E

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024977.2NP_001020148.1  calcium homeostasis modulator protein 5

      See identical proteins and their annotated locations for NP_001020148.1

      Status: VALIDATED

      Source sequence(s)
      BC089225
      UniProtKB/Swiss-Prot
      Q5FWS4
      UniProtKB/TrEMBL
      A6K3S5
      Related
      ENSRNOP00000054130.2, ENSRNOT00000057313.6
      Conserved Domains (1) summary
      pfam14798
      Location:4251
      Ca_hom_mod; Calcium homeostasis modulator

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      26609400..26615478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)