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    Morc2b microrchidia 2B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299555, updated on 9-Dec-2024

    Summary

    Symbol
    Morc2bprovided by RGD
    Full Name
    microrchidia 2Bprovided by RGD
    Primary source
    RGD:1564020
    See related
    EnsemblRapid:ENSRNOG00000004501 AllianceGenome:RGD:1564020
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564020
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in double-strand break repair involved in meiotic recombination; gamete generation; and homologous chromosome pairing at meiosis. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2Z. Orthologous to human MORC2 (MORC family CW-type zinc finger 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 109.8) See more
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    Genomic context

    See Morc2b in Genome Data Viewer
    Location:
    7q11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (12964822..12968902, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (12314341..12318421, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (15479754..15483834, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 563 Neighboring gene uncharacterized LOC120093536 Neighboring gene uncharacterized LOC134479824 Neighboring gene zinc finger protein 14-like Neighboring gene olfactory receptor 1090

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in double-strand break repair involved in meiotic recombination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in gamete generation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in homologous chromosome pairing at meiosis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    MORC family CW-type zinc finger protein 2B
    Names
    MORC family CW-type zinc finger protein 2B-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106764.1NP_001100234.1  MORC family CW-type zinc finger protein 2B

      See identical proteins and their annotated locations for NP_001100234.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474029
      UniProtKB/TrEMBL
      A6K983, D4A8J3
      Related
      ENSRNOP00000054417.2, ENSRNOT00000057608.6
      Conserved Domains (3) summary
      pfam07496
      Location:495541
      zf-CW; CW-type Zinc Finger
      pfam13589
      Location:29169
      HATPase_c_3; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
      cl02565
      Location:444576
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      12964822..12968902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)