Spata22 spermatogenesis associated 22 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Spata22provided by RGD
Official Full Name: spermatogenesis associated 22provided by RGD
Primary source: RGD:1565378
See related: EnsemblRapid:ENSRNOG00000037307 AllianceGenome:RGD:1565378
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Sgn; RGD1565378
Summary: Involved in spermatocyte division. Predicted to be located in chromosome. Orthologous to human SPATA22 (spermatogenesis associated 22). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 49.0) and Kidney (RPKM 36.9) See more
Orthologs: human mouse all
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Genomic context

Location:: 10q24

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (58443736..58461578)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (57945272..57963081)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (59893064..59910769)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Spata22 may function in regulating the post-invasion DNA synthesis through interacting with Rpa on the displaced strand.
Title: Genetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosis.
It plays an important role in meiotic prophase I and its deletion causes infertility in rats.
Title: Infertility associated with meiotic failure in the tremor rat (tm/tm) is caused by the deletion of spermatogenesis associated 22.

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within fertilization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within gamete generation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within homologous chromosome pairing at meiosis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within meiotic DNA repair synthesis	ISO Inferred from Sequence Orthology more info
involved_in regulation of meiotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of meiotic cell cycle	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within reproductive system development	ISO Inferred from Sequence Orthology more info
involved_in spermatocyte division	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chromosome	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: spermatogenesis-associated protein 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.