Rmdn1 regulator of microtubule dynamics 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rmdn1provided by RGD
Official Full Name: regulator of microtubule dynamics 1provided by RGD
Primary source: RGD:1563085
See related: EnsemblRapid:ENSRNOG00000025145 AllianceGenome:RGD:1563085
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Fam82b
Summary: Predicted to enable microtubule binding activity. Predicted to be located in microtubule and spindle pole. Predicted to be active in mitochondrion; mitotic spindle pole; and spindle microtubule. Orthologous to human RMDN1 (regulator of microtubule dynamics 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Heart (RPKM 395.9), Muscle (RPKM 372.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 5q13

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (37867172..37890826)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (33070267..33093922)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (33580891..33604564)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info
enables microtubule binding	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed
is_active_in mitotic spindle pole	IBA Inferred from Biological aspect of Ancestor more info
located_in mitotic spindle pole	IEA Inferred from Electronic Annotation more info
located_in mitotic spindle pole	ISO Inferred from Sequence Orthology more info
is_active_in spindle microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in spindle microtubule	IEA Inferred from Electronic Annotation more info
located_in spindle microtubule	ISO Inferred from Sequence Orthology more info
located_in spindle pole	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: regulator of microtubule dynamics protein 1

Names: RMD-1; family with sequence similarity 82, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031663.1 → NP_001026833.1 regulator of microtubule dynamics protein 1

See identical proteins and their annotated locations for NP_001026833.1

Status: PROVISIONAL

Source sequence(s)

BC098713

UniProtKB/Swiss-Prot

Q4G069

UniProtKB/TrEMBL

A6IIC7

Related

ENSRNOP00000030229.3, ENSRNOT00000036050.6

Conserved Domains (1) summary

sd00006
Location:204 → 254

TPR; TPR repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086023.1 Reference GRCr8

Range

37867172..37890826

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006237933.5 → XP_006237995.1 regulator of microtubule dynamics protein 1 isoform X1

UniProtKB/TrEMBL

A0A8I6G831, A6IIC7

Related

ENSRNOP00000082921.1, ENSRNOT00000100436.2

Conserved Domains (2) summary

sd00006
Location:140 → 169

TPR; TPR repeat [structural motif]

cl15239
Location:92 → 179

PLDc_SF; Catalytic domain of phospholipase D superfamily proteins