Fam151b family with sequence similarity 151, member B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Fam151bprovided by MGI
Official Full Name: family with sequence similarity 151, member Bprovided by MGI
Primary source: MGI:MGI:1921192
See related: Ensembl:ENSMUSG00000034334 AllianceGenome:MGI:1921192
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4930405M20Rik
Summary: Involved in photoreceptor cell development. Predicted to be active in extracellular space. Is expressed in brain; spinal cord; and testis. Orthologous to human FAM151B (family with sequence similarity 151 member B). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in testis adult (RPKM 3.8), bladder adult (RPKM 2.9) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 13 C3; 13 47.7 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (92586128..92620539, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (92449620..92484031, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.
Title: Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in photoreceptor cell development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein FAM151B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001163627.1 → NP_001157099.1 protein FAM151B

Status: VALIDATED

Source sequence(s)

AK015100, AK162422, BE944380, BY202398

Consensus CDS

CCDS49327.1

UniProtKB/Swiss-Prot

D3YUE4

Related

ENSMUSP00000045024.8, ENSMUST00000040106.9

Conserved Domains (1) summary

pfam10223
Location:29 → 263

DUF2181; Uncharacterized conserved protein (DUF2181)