Mfsd6l major facilitator superfamily domain containing 6-like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mfsd6lprovided by MGI
Official Full Name: major facilitator superfamily domain containing 6-likeprovided by MGI
Primary source: MGI:MGI:2384904
See related: Ensembl:ENSMUSG00000048329 AllianceGenome:MGI:2384904
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to be active in membrane. Orthologous to human MFSD6L (major facilitator superfamily domain containing 6 like). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human all
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Genomic context

Location:: 11 B3; 11 41.81 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (68447012..68449071)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (68556186..68558245)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Deficiency of MFSD6L, an acrosome membrane protein, causes oligoasthenoteratozoospermia in humans and mice.
Title: Deficiency of MFSD6L, an acrosome membrane protein, causes oligoasthenoteratozoospermia in humans and mice.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3) 1 citation

General gene information

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Markers

D10M11Mit28 (e-PCR)
- UniSTS:126486

D11Mit28 (e-PCR), detects polymorphism
- UniSTS:126486

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: major facilitator superfamily domain-containing protein 6-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146004.1 → NP_666116.1 major facilitator superfamily domain-containing protein 6-like

See identical proteins and their annotated locations for NP_666116.1

Status: PROVISIONAL

Source sequence(s)

BC024997

Consensus CDS

CCDS24867.1

UniProtKB/Swiss-Prot

Q8R3N2

Related

ENSMUSP00000061601.7, ENSMUST00000053211.8

Conserved Domains (2) summary

cd06174
Location:365 → 521

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

cl21472
Location:28 → 87

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...