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    Cdcp3 CUB domain containing protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 71395, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cdcp3provided by MGI
    Official Full Name
    CUB domain containing protein 3provided by MGI
    Primary source
    MGI:MGI:1918645
    See related
    Ensembl:ENSMUSG00000006204 AllianceGenome:MGI:1918645
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5430419D17Rik
    Summary
    Predicted to be located in membrane. Orthologous to human DMBT1L1 (deleted in malignant brain tumors 1 like 1 (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Cdcp3 in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    69
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (130776131..130908181)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (131174402..131306452)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4933402N03 gene Neighboring gene RIKEN cDNA 1700029B22 gene Neighboring gene deleted in malignant brain tumors 1 pseudogene Neighboring gene CUB and zona pellucida-like domains 1 Neighboring gene family with sequence similarity 24 member B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Deleted in malignant brain tumors-1 protein (DMBT1): a pattern recognition receptor with multiple binding sites. Ligtenberg AJ, et al. Int J Mol Sci, 2010. PMID 21614203, Free PMC Article
    2. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nelson PS, et al. Nucleic Acids Res, 2002 Jan 1. PMID 11752298, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative DMBT1-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370825.1 → NP_001357754.1  putative DMBT1-like protein isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC110885
      UniProtKB/TrEMBL
      A0A1L1SUH6
      Related
      ENSMUSP00000150784.3, ENSMUST00000208921.4
      Conserved Domains (4) summary
      smart00202
      Location:1272 → 1372
      SR; Scavenger receptor Cys-rich
      cd00041
      Location:1150 → 1260
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      pfam00100
      Location:2212 → 2450
      Zona_pellucida; Zona pellucida-like domain
      cl00049
      Location:272 → 375
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

    2. NM_175166.3 → NP_780375.2  putative DMBT1-like protein isoform 1 precursor

      See identical proteins and their annotated locations for NP_780375.2

      Status: VALIDATED

      Source sequence(s)
      AC110885, AK035662
      Consensus CDS
      CCDS21911.1
      UniProtKB/Swiss-Prot
      E9QN00, Q8BZE1
      Related
      ENSMUSP00000061529.6, ENSMUST00000050586.6
      Conserved Domains (3) summary
      smart00202
      Location:144 → 244
      SR; Scavenger receptor Cys-rich
      cd00041
      Location:556 → 666
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cl00049
      Location:272 → 375
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      130776131..130908181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BZE1.2 GenPept UniProtKB/Swiss-Prot:Q8BZE1

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