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    Rbm34 RNA binding motif protein 34 [ Mus musculus (house mouse) ]

    Gene ID: 52202, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Rbm34provided by MGI
    Official Full Name
    RNA binding motif protein 34provided by MGI
    Primary source
    MGI:MGI:1098653
    See related
    Ensembl:ENSMUSG00000033931 AllianceGenome:MGI:1098653
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6330444B11; D8Ertd233e; 4930547K05Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in chromosome and nucleoplasm. Predicted to be active in nucleolus. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; integumental system; and nervous system. Orthologous to human RBM34 (RNA binding motif protein 34). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 5.7), CNS E11.5 (RPKM 3.7) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rbm34 in Genome Data Viewer
    Location:
    8 E2; 8 74.64 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (127673922..127697799, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (126947172..126971127, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene translocase of outer mitochondrial membrane 20 Neighboring gene predicted gene, 53208 Neighboring gene STARR-positive B cell enhancer ABC_E6707 Neighboring gene predicted gene, 26397 Neighboring gene STARR-seq mESC enhancer starr_23083 Neighboring gene STARR-positive B cell enhancer ABC_E6708 Neighboring gene predicted gene, 29688 Neighboring gene predicted gene, 38574

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. McKee AE, et al. BMC Dev Biol, 2005 Jul 20. PMID 16033648, Free PMC Article
    2. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Rudra D, et al. Nat Immunol, 2012 Oct. PMID 22922362, Free PMC Article
    3. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
    4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein 34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374800.1 → NP_001361729.1  RNA-binding protein 34 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC115706, AC119874
      Consensus CDS
      CCDS90487.1
      UniProtKB/TrEMBL
      A0A1D5RLR3
      Related
      ENSMUSP00000148473.2, ENSMUST00000212618.2
      Conserved Domains (2) summary
      cd12395
      Location:272 → 344
      RRM2_RBM34; RNA recognition motif 2 in RNA-binding protein 34 (RBM34) and similar proteins
      cl17169
      Location:189 → 260
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. NM_172762.3 → NP_766350.2  RNA-binding protein 34 isoform 1

      See identical proteins and their annotated locations for NP_766350.2

      Status: VALIDATED

      Source sequence(s)
      AC119874, BC141278
      Consensus CDS
      CCDS22787.1
      UniProtKB/Swiss-Prot
      B2RUP0, Q8C5L7
      Related
      ENSMUSP00000048450.7, ENSMUST00000045994.8
      Conserved Domains (2) summary
      cd12394
      Location:189 → 280
      RRM1_RBM34; RNA recognition motif 1 in RNA-binding protein 34 (RBM34) and similar proteins
      cd12395
      Location:292 → 364
      RRM2_RBM34; RNA recognition motif 2 in RNA-binding protein 34 (RBM34) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      127673922..127697799 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C5L7.2 GenPept UniProtKB/Swiss-Prot:Q8C5L7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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