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    tnfsf10l3 tumor necrosis factor (ligand) superfamily, member 10 like 3 [ Danio rerio (zebrafish) ]

    Gene ID: 562262, updated on 9-Dec-2024

    Summary

    Official Symbol
    tnfsf10l3provided by ZNC
    Official Full Name
    tumor necrosis factor (ligand) superfamily, member 10 like 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070606-1
    See related
    Ensembl:ENSDARG00000032746 AllianceGenome:ZFIN:ZDB-GENE-070606-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dl1b
    Summary
    Predicted to enable cytokine activity. Predicted to be involved in cell surface receptor signaling pathway; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to act upstream of or within immune response. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in anterior lateral line neuromast; posterior lateral line neuromast; and posterior lateral line primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See tnfsf10l3 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (30701902..30714555, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (30665207..30677860, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene si:dkey-22f5.9 Neighboring gene uncharacterized LOC137488829 Neighboring gene chloride channel, voltage-sensitive 5a Neighboring gene xrcc1 N-terminal domain containing 1 Neighboring gene transient receptor potential cation channel subfamily C member 2b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cytokine activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of canonical NF-kappaB signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of extrinsic apoptotic signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tumor necrosis factor (ligand) superfamily, member 10 like 3
    Names
    TNFSF10-3
    death ligand 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042713.1NP_001036178.1  tumor necrosis factor (ligand) superfamily, member 10 like 3

      See identical proteins and their annotated locations for NP_001036178.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ812113
      UniProtKB/TrEMBL
      B3DHP1, F6P519, Q0PKX9
      Related
      ENSDARP00000112169.2, ENSDART00000128011.3
      Conserved Domains (1) summary
      pfam00229
      Location:158286
      TNF; TNF(Tumour Necrosis Factor) family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      30701902..30714555 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)