ncapd3 non-SMC condensin II complex, subunit D3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ncapd3provided by ZNC
Official Full Name: non-SMC condensin II complex, subunit D3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-737
See related: Ensembl:ENSDARG00000034773 AllianceGenome:ZFIN:ZDB-GENE-040426-737
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55549; id:ibd2253
Summary: Predicted to enable histone binding activity. Predicted to be involved in meiotic chromosome condensation and mitotic chromosome condensation. Predicted to act upstream of or within chromosome condensation. Predicted to be located in nucleus. Predicted to be part of condensin complex. Predicted to be active in condensed chromosome, centromeric region. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD3 (non-SMC condensin II complex subunit D3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 35

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (21540453..21563040, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (20847516..20870103, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fi53b10.x1 (e-PCR)
- UniSTS:197682

fi67g03.y1 (e-PCR)
- UniSTS:197840

fc25b04.x1 (e-PCR)
- UniSTS:193237

fc25b04.x1 (e-PCR)
- UniSTS:193238

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables histone binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chromosome condensation	IEA Inferred from Electronic Annotation more info
involved_in meiotic chromosome condensation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic chromosome condensation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitotic chromosome condensation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in condensed chromosome, centromeric region	IBA Inferred from Biological aspect of Ancestor more info
part_of condensin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of condensin complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: condensin-2 complex subunit D3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200330.1 → NP_956624.1 condensin-2 complex subunit D3

See identical proteins and their annotated locations for NP_956624.1

Status: PROVISIONAL

Source sequence(s)

BC052478

UniProtKB/TrEMBL

Q7SZF2

Related

ENSDARP00000049571.3, ENSDART00000049572.4

Conserved Domains (2) summary

pfam12717
Location:948 → 1144

Cnd1; non-SMC mitotic condensation complex subunit 1

sd00044
Location:538 → 568

HEAT; HEAT repeat [structural motif]