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    snx9b sorting nexin 9b [ Danio rerio (zebrafish) ]

    Gene ID: 558917, updated on 9-Dec-2024

    Summary

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    Official Symbol
    snx9bprovided by ZNC
    Official Full Name
    sorting nexin 9bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031118-50
    See related
    Ensembl:ENSDARG00000069302 AllianceGenome:ZFIN:ZDB-GENE-031118-50
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    snx9l; wu:fj22c06; wu:fj94b09; wu:fk76d01; si:dkeyp-70e6.2
    Summary
    Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including cleavage furrow formation; endosomal transport; and plasma membrane tubulation. Predicted to act upstream of or within intracellular protein transport and mitotic cytokinesis. Predicted to be located in cytoplasmic vesicle membrane. Predicted to be active in cytoplasmic vesicle and plasma membrane. Orthologous to human SNX9 (sorting nexin 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See snx9b in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (43016437..43079494, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (43119359..43182472, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene EFR3 homolog Bb (S. cerevisiae) Neighboring gene si:ch211-203k16.3 Neighboring gene proopiomelanocortin b Neighboring gene monooxygenase, DBH-like 1, like Neighboring gene dual specificity phosphatase 23a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish. Xu L, et al. Hepatology, 2012 Jun. PMID 22213104
    2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC111948

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sorting nexin-9b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030124.1 → NP_001025295.1  sorting nexin-9b

      See identical proteins and their annotated locations for NP_001025295.1

      Status: PROVISIONAL

      Source sequence(s)
      AL845420
      UniProtKB/TrEMBL
      B3DJS3, Q5SPP2
      Related
      ENSDARP00000060981.4, ENSDART00000060982.6
      Conserved Domains (3) summary
      cd07285
      Location:235 → 360
      PX_SNX9; The phosphoinositide binding Phox Homology domain of Sorting Nexin 9
      cd07668
      Location:372 → 581
      BAR_SNX9; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 9
      cd11898
      Location:4 → 60
      SH3_SNX9; Src Homology 3 domain of Sorting nexin 9

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      43016437..43079494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021468449.2 → XP_021324124.1  sorting nexin-9b isoform X3

      UniProtKB/TrEMBL
      A0A8M9PHD2
      Conserved Domains (3) summary
      cd07285
      Location:247 → 372
      PX_SNX9; The phosphoinositide binding Phox Homology domain of Sorting Nexin 9
      cd07668
      Location:384 → 593
      BAR_SNX9; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 9
      cd11898
      Location:4 → 60
      SH3_SNX9; Src Homology 3 domain of Sorting nexin 9

    2. XM_005170181.5 → XP_005170238.1  sorting nexin-9b isoform X2

      UniProtKB/TrEMBL
      A0A8M2BI00
      Conserved Domains (3) summary
      cd07285
      Location:262 → 387
      PX_SNX9; The phosphoinositide binding Phox Homology domain of Sorting Nexin 9
      cd07668
      Location:399 → 608
      BAR_SNX9; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 9
      cd11898
      Location:4 → 60
      SH3_SNX9; Src Homology 3 domain of Sorting nexin 9

    3. XM_021468448.2 → XP_021324123.1  sorting nexin-9b isoform X1

      UniProtKB/TrEMBL
      A0A8M9PBT0
      Conserved Domains (3) summary
      cd07285
      Location:274 → 399
      PX_SNX9; The phosphoinositide binding Phox Homology domain of Sorting Nexin 9
      cd07668
      Location:411 → 620
      BAR_SNX9; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 9
      cd11898
      Location:4 → 60
      SH3_SNX9; Src Homology 3 domain of Sorting nexin 9

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395344.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      162441..224016 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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