wdr1 WD repeat domain 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: wdr1provided by ZNC
Official Full Name: WD repeat domain 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-804
See related: AllianceGenome:ZFIN:ZDB-GENE-040426-804
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55793; zgc:77547; unm_t31103; wu:fa66e09
Summary: Is expressed in ectoderm; epidermis; nervous system; and solid lens vesicle. Orthologous to human WDR1 (WD repeat domain 1). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (164434..187551)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (99686..116100)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_008805531.1 (1..1000, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

coronin 1A depletion restores the nuclear stability and viability of Aip1/Wdr1-deficient neutrophils
Title: Coronin 1A depletion restores the nuclear stability and viability of Aip1/Wdr1-deficient neutrophils.

Submit: New GeneRIF Correction

General gene information

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Markers

G46496 (e-PCR)
- UniSTS:107298

fl05f06.x1 (e-PCR)
- UniSTS:201902

fa66e09.s1 (e-PCR)
- UniSTS:189614

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in actin filament depolymerization	IBA Inferred from Biological aspect of Ancestor more info
involved_in locomotion	IBA Inferred from Biological aspect of Ancestor more info
involved_in sarcomere organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cortical actin cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: WD repeat-containing protein 1

Names: unm t31103

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201039.1 → NP_957333.1 WD repeat-containing protein 1

See identical proteins and their annotated locations for NP_957333.1

Status: PROVISIONAL

Source sequence(s)

BC045455

UniProtKB/TrEMBL

Q7ZVQ3

Conserved Domains (4) summary

COG2319
Location:54 → 426

WD40; WD40 repeat [General function prediction only]

cd00200
Location:53 → 389

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:62 → 100

7WD40; WD40 repeat [structural motif]

cl02567
Location:312 → 602

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...