rpl5b ribosomal protein L5b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rpl5bprovided by ZNC
Official Full Name: ribosomal protein L5bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040625-93
See related: Ensembl:ENSDARG00000015862 AllianceGenome:ZFIN:ZDB-GENE-040625-93
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rpl5; fj02g05; zgc:86854; wu:fj02g05
Summary: Predicted to enable 5S rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 6; T-cell acute lymphoblastic leukemia; and glioblastoma. Orthologous to human RPL5 (ribosomal protein L5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 6

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (29086613..29097390)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (29096052..29106829)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb10f02.x1 (e-PCR)
- UniSTS:190006

fk87c11.x1 (e-PCR)
- UniSTS:201653

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 5S rRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables 5S rRNA binding	IEA Inferred from Electronic Annotation more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ribosomal large subunit assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 60S ribosomal protein L5b

NP_001002106.1

EC 3.6.5.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002106.1 → NP_001002106.1 60S ribosomal protein L5b

See identical proteins and their annotated locations for NP_001002106.1

Status: PROVISIONAL

Source sequence(s)

BC071498

UniProtKB/TrEMBL

F6NIG3, Q6DGX7, Q6IQB1

Related

ENSDARP00000106359.2, ENSDART00000127695.3

Conserved Domains (3) summary

PTZ00069
Location:1 → 295

PTZ00069; 60S ribosomal protein L5; Provisional

pfam00861
Location:26 → 173

Ribosomal_L18p; Ribosomal L18p/L5e family

pfam14204
Location:192 → 282

Ribosomal_L18_c; Ribosomal L18 C-terminal region