gpr85 G protein-coupled receptor 85 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gpr85provided by ZNC
Official Full Name: G protein-coupled receptor 85provided by ZNC
Primary source: ZFIN:ZDB-GENE-000710-2
See related: Ensembl:ENSDARG00000068701 AllianceGenome:ZFIN:ZDB-GENE-000710-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: serb2; sreb2; zSREB2
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in central nervous system and retina. Orthologous to human GPR85 (G protein-coupled receptor 85). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (6643514..6647605)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (6634944..6639035)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: probable G protein-coupled receptor 85

Names: brain super conserved receptor 2; super conserved receptor expressed in brain 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131499.2 → NP_571574.1 probable G protein-coupled receptor 85

See identical proteins and their annotated locations for NP_571574.1

Status: PROVISIONAL

Source sequence(s)

BC054645

UniProtKB/Swiss-Prot

A4KUT3, Q1L937, Q9I919

Related

ENSDARP00000090236.3, ENSDART00000099462.4

Conserved Domains (2) summary

cd14964
Location:24 → 48

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:22 → 351

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily