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    sem1 SEM1 26S proteasome subunit [ Danio rerio (zebrafish) ]

    Gene ID: 322269, updated on 9-Dec-2024

    Summary

    Official Symbol
    sem1provided by ZNC
    Official Full Name
    SEM1 26S proteasome subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-988
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030131-988
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    shfm1; Shfdg1; zgc:56203; zgc:85901; wu:fb55c02
    Summary
    Predicted to be involved in double-strand break repair via homologous recombination. Predicted to be located in nucleus. Predicted to be part of proteasome complex. Orthologous to human SEM1 (SEM1 26S proteasome subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See sem1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (41401135..41405188, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (41816080..41820133, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene dynein cytoplasmic 1 intermediate chain 1 Neighboring gene solute carrier family 25 member 13 Neighboring gene distal-less homeobox 6a Neighboring gene distal-less homeobox 5a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mRNA export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA export from nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within proteasome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proteasome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proteasome complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of proteasome complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proteasome regulatory particle, lid subcomplex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    26S proteasome complex subunit SEM1
    Names
    SEM1 26S proteasome complex subunit
    split hand/foot deleted gene 1
    split hand/foot malformation (ectrodactyly) type 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199593.3NP_955887.1  26S proteasome complex subunit SEM1

      See identical proteins and their annotated locations for NP_955887.1

      Status: VALIDATED

      Source sequence(s)
      CU634012, EH550922
      UniProtKB/TrEMBL
      Q7ZU84
      Conserved Domains (1) summary
      pfam05160
      Location:2362
      DSS1_SEM1; DSS1/SEM1 family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      41401135..41405188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)