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    klhl26 kelch-like family member 26 [ Danio rerio (zebrafish) ]

    Gene ID: 558035, updated on 9-Dec-2024

    Summary

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    Official Symbol
    klhl26provided by ZNC
    Official Full Name
    kelch-like family member 26provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5975
    See related
    Ensembl:ENSDARG00000053876 AllianceGenome:ZFIN:ZDB-GENE-030131-5975
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fi20e10; wu:fi28a03; zgc:153248; si:ch211-255d18.7
    Summary
    Orthologous to human KLHL26 (kelch like family member 26). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See klhl26 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (6882117..6891090)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (6872296..6881172)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 Neighboring gene uncharacterized LOC137496669 Neighboring gene CREB regulated transcription coactivator 1b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Structure, evolution and expression of zebrafish cartilage oligomeric matrix protein (COMP, TSP5). CRISPR-Cas mutants show a dominant phenotype in myosepta. Forte-Gomez HF, et al. Front Endocrinol (Lausanne), 2022. PMID 36452329, Free PMC Article
    2. Zebrafish Tric-b is required for skeletal development and bone cells differentiation. Tonelli F, et al. Front Endocrinol (Lausanne), 2023. PMID 36755921, Free PMC Article
    3. Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin. Feiner N, et al. Genome Biol Evol, 2013. PMID 23843192, Free PMC Article
    4. Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. Liu Z, et al. J Biol Chem, 2011 Aug 12. PMID 21669877, Free PMC Article
    5. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0469, MGC153248

    General protein information

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    Preferred Names
    kelch-like protein 26
    Names
    kelch-like 26

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044853.3 → NP_001038318.2  kelch-like protein 26

      See identical proteins and their annotated locations for NP_001038318.2

      Status: PROVISIONAL

      Source sequence(s)
      BC124287
      UniProtKB/TrEMBL
      Q08CD3
      Related
      ENSDARP00000070477.4, ENSDART00000075998.6
      Conserved Domains (7) summary
      smart00612
      Location:404 → 450
      Kelch; Kelch domain
      PHA03098
      Location:55 → 596
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:342 → 389
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:43 → 147
      BTB; BTB/POZ domain
      pfam01344
      Location:487 → 536
      Kelch_1; Kelch motif
      pfam07707
      Location:155 → 256
      BACK; BTB And C-terminal Kelch
      pfam13964
      Location:441 → 488
      Kelch_6; Kelch motif

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      6882117..6891090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068224182.1 → XP_068080283.1  kelch-like protein 26 isoform X1

      UniProtKB/Swiss-Prot
      Q5RGB8
      Related
      ENSDARP00000115562.1, ENSDART00000144181.2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5RGB8.1 GenPept UniProtKB/Swiss-Prot:Q5RGB8

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