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    ilrun inflammation and lipid regulator with UBA-like and NBR1-like domains [ Danio rerio (zebrafish) ]

    Gene ID: 541415, updated on 9-Dec-2024

    Summary

    Official Symbol
    ilrunprovided by ZNC
    Official Full Name
    inflammation and lipid regulator with UBA-like and NBR1-like domainsprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050320-117
    See related
    Ensembl:ENSDARG00000078075 AllianceGenome:ZFIN:ZDB-GENE-050320-117
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:101577
    Summary
    Predicted to enable ubiquitin binding activity. Predicted to be involved in macroautophagy. Predicted to act upstream of or within innate immune response. Predicted to be located in cytoplasm and nucleus. Predicted to be active in phagophore assembly site. Orthologous to human ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ilrun in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (54325008..54348612, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (54316900..54340511, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene protein kinase C and casein kinase substrate in neurons 1b Neighboring gene SAM pointed domain containing ETS transcription factor Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1Ab Neighboring gene small nuclear ribonucleoprotein polypeptide C

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in macroautophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in phagophore assembly site IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein ILRUN
    Names
    uncharacterized protein C6orf106 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013542.2NP_001013560.2  protein ILRUN

      Status: VALIDATED

      Source sequence(s)
      CU856151
      UniProtKB/Swiss-Prot
      Q5BL31
      UniProtKB/TrEMBL
      A0A8M3B3Q8, F1R890
      Related
      ENSDARP00000129179.1, ENSDART00000156501.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      54325008..54348612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_011015813.1 RNA Sequence