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    hmg20a high mobility group 20A [ Danio rerio (zebrafish) ]

    Gene ID: 326908, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hmg20aprovided by ZNC
    Official Full Name
    high mobility group 20Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5107
    See related
    Ensembl:ENSDARG00000031198 AllianceGenome:ZFIN:ZDB-GENE-030131-5107
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fe47h11; wu:fe47h11; zgc:162335
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to be active in nucleus. Is expressed in telencephalon. Orthologous to human HMG20A (high mobility group 20A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See hmg20a in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (7241133..7336346)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (7147511..7162306)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene mucin 5d Neighboring gene leucine rich repeat and Ig domain containing 1a Neighboring gene pseudopodium-enriched atypical kinase 1 Neighboring gene ubiquitin associated protein 1-like a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. O'Hare EA, et al. Mol Endocrinol, 2016 Apr. PMID 26963759, Free PMC Article
    2. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    high mobility group protein 20A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089334.1 → NP_001082803.1  high mobility group protein 20A

      See identical proteins and their annotated locations for NP_001082803.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133951
      UniProtKB/TrEMBL
      A0A8M6Z4B9, A3KNQ1
      Related
      ENSDARP00000095483.3, ENSDART00000104712.5
      Conserved Domains (1) summary
      cd01390
      Location:45 → 110
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      7241133..7336346
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068217327.1 → XP_068073428.1  high mobility group protein 20A isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z4B9, A3KNQ1

    2. XM_068217326.1 → XP_068073427.1  high mobility group protein 20A isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z4B9, A3KNQ1
      Related
      ENSDARP00000147000.1, ENSDART00000190501.1

    3. XM_068217325.1 → XP_068073426.1  high mobility group protein 20A isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z4B9, A3KNQ1

    4. XM_068217329.1 → XP_068073430.1  high mobility group protein 20A isoform X3

      UniProtKB/TrEMBL
      A0A8M2BLH9

    5. XM_068217324.1 → XP_068073425.1  high mobility group protein 20A isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z4B9, A3KNQ1
      Related
      ENSDARP00000157579.1, ENSDART00000190588.1

    6. XM_068217328.1 → XP_068073429.1  high mobility group protein 20A isoform X3

      UniProtKB/TrEMBL
      A0A8M2BLH9

    7. XM_005174266.5 → XP_005174323.1  high mobility group protein 20A isoform X3

      UniProtKB/TrEMBL
      A0A8M2BLH9
      Conserved Domains (1) summary
      cd01390
      Location:45 → 110
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

    8. XM_017354056.3 → XP_017209545.1  high mobility group protein 20A isoform X2

      UniProtKB/TrEMBL
      A0A8M6Z4B9, A3KNQ1
      Conserved Domains (1) summary
      cd01390
      Location:45 → 110
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    Nucleotide Protein
    Heading Accession and Version

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