scaf4a SR-related CTD-associated factor 4a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: scaf4aprovided by ZNC
Official Full Name: SR-related CTD-associated factor 4aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9003
See related: Ensembl:ENSDARG00000077093 AllianceGenome:ZFIN:ZDB-GENE-030131-9003
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa96d07; wu:fa96d07; si:dkey-50p8.3
Summary: Predicted to enable RNA binding activity and RNA polymerase II C-terminal domain phosphoserine binding activity. Predicted to be involved in negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled. Predicted to be active in nucleus. Orthologous to human SCAF4 (SR-related CTD associated factor 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (25700812..25716850, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (25739082..25755160, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

SCAF4 variants associated with focal epilepsy accompanied by multisystem disorders.
Title: SCAF4 variants associated with focal epilepsy accompanied by multisystem disorders.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II C-terminal domain phosphoserine binding	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

Preferred Names: SR-related and CTD-associated factor 4; splicing factor, arginine/serine-rich 15

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The following sections contain reference sequences that belong to a specific genome build. Explain