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    cops8 COP9 signalosome subunit 8 [ Danio rerio (zebrafish) ]

    Gene ID: 393198, updated on 9-Dec-2024

    Summary

    Official Symbol
    cops8provided by ZNC
    Official Full Name
    COP9 signalosome subunit 8provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-982
    See related
    Ensembl:ENSDARG00000024846 AllianceGenome:ZFIN:ZDB-GENE-040426-982
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56319; zgc:86840
    Summary
    Predicted to act upstream of or within COP9 signalosome assembly and protein deneddylation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of COP9 signalosome. Orthologous to human COPS8 (COP9 signalosome subunit 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cops8 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (23895743..23906205)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (24084874..24095336)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 124 member A Neighboring gene ankyrin repeat and SOCS box containing 18 Neighboring gene tripartite motif containing 63b Neighboring gene collagen, type VI, alpha 3 Neighboring gene melanophilin b Neighboring gene prolactin releasing hormone

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC56319, MGC86840

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within COP9 signalosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein deneddylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of COP9 signalosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of COP9 signalosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    COP9 signalosome complex subunit 8
    Names
    COP9 constitutive photomorphogenic homolog subunit 8
    signalosome subunit 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200229.2NP_956523.1  COP9 signalosome complex subunit 8

      See identical proteins and their annotated locations for NP_956523.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046071
      UniProtKB/Swiss-Prot
      Q7ZUZ0
      Related
      ENSDARP00000037304.6, ENSDART00000034686.7
      Conserved Domains (1) summary
      pfam10075
      Location:32164
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      23895743..23906205
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394753.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      14903..25365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)