etf1b eukaryotic translation termination factor 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: etf1bprovided by ZNC
Official Full Name: eukaryotic translation termination factor 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-021029-1
See related: Ensembl:ENSDARG00000043976 AllianceGenome:ZFIN:ZDB-GENE-021029-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: eRF1; etf1; zeh0057; hm:zeh0057; wu:fa19e07; wu:fi31f01
Summary: Predicted to enable sequence-specific mRNA binding activity and translation release factor activity, codon specific. Acts upstream of or within brain development. Predicted to be located in cytoplasm. Predicted to be part of translation release factor complex. Predicted to be active in cytosol. Orthologous to human ETF1 (eukaryotic translation termination factor 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 10

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (21434720..21443772)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (21477339..21486391)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb52g05.x1 (e-PCR)
- UniSTS:203293

STS43H03.02 (e-PCR)
- UniSTS:205707

fi31f01.x1 (e-PCR)
- UniSTS:197263

fa19e07.s1 (e-PCR)
- UniSTS:202448

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables sequence-specific mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables translation release factor activity	IEA Inferred from Electronic Annotation more info
enables translation release factor activity, codon specific	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within brain development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cytoplasmic translational termination	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translational termination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
part_of translation release factor complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: eukaryotic peptide chain release factor subunit 1b

Names: etID39694.10; eukaryotic translation termination factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201460.2 → NP_958868.1 eukaryotic peptide chain release factor subunit 1b

See identical proteins and their annotated locations for NP_958868.1

Status: PROVISIONAL

Source sequence(s)

AY398343

UniProtKB/TrEMBL

Q6NYI2, Q803E5

Related

ENSDARP00000064557.3, ENSDART00000064558.4

Conserved Domains (1) summary

COG1503
Location:11 → 424

eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007121.7 Reference GRCz11 Primary Assembly

Range

21434720..21443772

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021479101.2 → XP_021334776.1 eukaryotic peptide chain release factor subunit 1b isoform X1

UniProtKB/TrEMBL

Q6NYI2, Q803E5

Conserved Domains (1) summary

COG1503
Location:11 → 424

eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]