atad3 ATPase family AAA domain containing 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atad3provided by ZNC
Official Full Name: ATPase family AAA domain containing 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1826
See related: AllianceGenome:ZFIN:ZDB-GENE-040426-1826
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: atad3b; zgc:77371
Summary: Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in anatomical structure morphogenesis. Predicted to be located in membrane and mitochondrial nucleoid. Human ortholog(s) of this gene implicated in Harel-Yoon syndrome and neonatal lethal pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency syndrome. Orthologous to several human genes including ATAD3B (ATPase family AAA domain containing 3B). [provided by Alliance of Genome Resources, Dec 2024]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (2008..7139, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (53306..58437, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

G41710 (e-PCR)
- UniSTS:36911

fd17g06.y1 (e-PCR)
- UniSTS:195230

fj23b10.y1 (e-PCR)
- UniSTS:198815

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in mitochondrion organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial nucleoid	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATPase family AAA domain containing 3

Names: ATPase family, AAA domain containing 3B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205703.1 → NP_991266.1 ATPase family AAA domain containing 3

See identical proteins and their annotated locations for NP_991266.1

Status: PROVISIONAL

Source sequence(s)

BC065962

UniProtKB/TrEMBL

Q6NZU8

Conserved Domains (3) summary

smart00382
Location:340 → 467

AAA; ATPases associated with a variety of cellular activities

pfam00004
Location:342 → 467

AAA; ATPase family associated with various cellular activities (AAA)

pfam12037
Location:35 → 280

DUF3523; Domain of unknown function (DUF3523)