si:dkey-7n6.2 si:dkey-7n6.2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: si:dkey-7n6.2provided by ZNC
Official Full Name: si:dkey-7n6.2provided by ZNC
Primary source: ZFIN:ZDB-GENE-091204-262
See related: Ensembl:ENSDARG00000094602 AllianceGenome:ZFIN:ZDB-GENE-091204-262
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable cAMP-dependent protein kinase inhibitor activity. Predicted to act upstream of or within negative regulation of protein kinase activity. Predicted to be active in cytoplasm and nucleus. Orthologous to human PKIA (cAMP-dependent protein kinase inhibitor alpha). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (22759451..22769996)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (22614277..22624822)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cAMP-dependent protein kinase inhibitor activity	IEA Inferred from Electronic Annotation more info
enables protein kinase inhibitor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of protein kinase activity	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cAMP-dependent protein kinase inhibitor alpha

Names: cAMP-dependent protein kinase inhibitor alpha-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199998.2 → NP_001186927.1 cAMP-dependent protein kinase inhibitor alpha

Status: VALIDATED

Source sequence(s)

BX942812, EH436759, EH460921, EH554565

UniProtKB/TrEMBL

A0A8M1NWK5

Related

ENSDARP00000113129.1, ENSDART00000135392.2

Conserved Domains (1) summary

pfam02827
Location:2 → 70

PKI; cAMP-dependent protein kinase inhibitor