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    abhd14b abhydrolase domain containing 14B [ Danio rerio (zebrafish) ]

    Gene ID: 393338, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abhd14bprovided by ZNC
    Official Full Name
    abhydrolase domain containing 14Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1342
    See related
    Ensembl:ENSDARG00000100531 AllianceGenome:ZFIN:ZDB-GENE-040426-1342
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:64031
    Summary
    Predicted to enable hydrolase activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human ABHD14B (abhydrolase domain containing 14B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See abhd14b in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (53416464..53435711)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (53428276..53435333)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene si:ch211-161c3.5 Neighboring gene si:ch211-161c3.6 Neighboring gene macrophage stimulating 1 Neighboring gene calcium channel, voltage-dependent, alpha 2/delta subunit 2a Neighboring gene uncharacterized LOC137496028 Neighboring gene hyaluronidase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. miR-142-3p acts as an essential modulator of neutrophil development in zebrafish. Fan HB, et al. Blood, 2014 Aug 21. PMID 24990885
    2. An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as reduced host immune response in angiogenesis and migration. Mohseny AB, et al. J Pathol, 2012 Jun. PMID 22297719
    3. Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Giffen KP, et al. Front Neurosci, 2019. PMID 31680844, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC64031

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative protein-lysine deacylase ABHD14B
    NP_956661.1
    XP_068077776.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200367.1 → NP_956661.1  putative protein-lysine deacylase ABHD14B

      See identical proteins and their annotated locations for NP_956661.1

      Status: PROVISIONAL

      Source sequence(s)
      BC053212
      UniProtKB/TrEMBL
      A0A8M1PED8, Q7T387
      Related
      ENSDARP00000135162.1, ENSDART00000165067.2
      Conserved Domains (2) summary
      COG0596
      Location:23 → 212
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      pfam12695
      Location:37 → 191
      Abhydrolase_5; Alpha/beta hydrolase family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      53416464..53435711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221675.1 → XP_068077776.1  putative protein-lysine deacylase ABHD14B isoform X1

      UniProtKB/TrEMBL
      A0A8M1PED8, Q7T387
    Nucleotide Protein Strain
    Heading Accession and Version

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