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    cyp8b1.3 cytochrome P450 family 8 subfamily B member 1, tandem duplicate 3 [ Danio rerio (zebrafish) ]

    Gene ID: 447848, updated on 9-Dec-2024

    Summary

    Official Symbol
    cyp8b1.3provided by ZNC
    Official Full Name
    cytochrome P450 family 8 subfamily B member 1, tandem duplicate 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-153
    See related
    Ensembl:ENSDARG00000097559 AllianceGenome:ZFIN:ZDB-GENE-040912-153
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cyp8b3; zgc:92214
    Summary
    Predicted to enable sterol 12-alpha-hydroxylase activity. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human CYP8B1 (cytochrome P450 family 8 subfamily B member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cyp8b1.3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (3468069..3470019)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (3636890..3638840)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene atypical chemokine receptor 2 Neighboring gene cytochrome P450 family 8 subfamily B member 1, tandem duplicate 1 Neighboring gene cytochrome P450 family 8 subfamily B member 1, tandem duplicate 2 Neighboring gene gap junction protein gamma 2 Neighboring gene zgc:92744

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
     
    enables sterol 12-alpha-hydroxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome P450 8B3
    Names
    cytochrome P450, family 8, subfamily B, polypeptide 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004587.2NP_001004587.2  cytochrome P450 8B3

      Status: VALIDATED

      Source sequence(s)
      BC081623, CF347548, CF347918, CN507547
      UniProtKB/TrEMBL
      A0A2R8QC82, A0A8M1N263, Q66HY4
      Related
      ENSDARP00000152282.1, ENSDART00000012143.10
      Conserved Domains (1) summary
      cl12078
      Location:33503
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      3468069..3470019
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)