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    derl2 derlin 2 [ Danio rerio (zebrafish) ]

    Gene ID: 554093, updated on 9-Dec-2024

    Summary

    Official Symbol
    derl2provided by ZNC
    Official Full Name
    derlin 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-90
    See related
    Ensembl:ENSDARG00000042401 AllianceGenome:ZFIN:ZDB-GENE-050522-90
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:110436
    Summary
    Predicted to enable signal recognition particle binding activity. Predicted to be involved in ERAD pathway and endoplasmic reticulum unfolded protein response. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DERL2 (derlin 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See derl2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (58997213..59009175)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (58327504..58339466)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene melanoma cell adhesion molecule a Neighboring gene MIS12 kinetochore complex component Neighboring gene SLP adaptor and CSK interacting membrane protein Neighboring gene rabaptin, RAB GTPase binding effector protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in ERAD pathway  
    involved_in endoplasmic reticulum unfolded protein response  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum  
    is_active_in endoplasmic reticulum membrane  
    located_in membrane  

    General protein information

    Preferred Names
    derlin-2
    Names
    Der1-like domain family, member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024395.1 → NP_001019566.1  derlin-2

      See identical proteins and their annotated locations for NP_001019566.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095262
      UniProtKB/TrEMBL
      B2GRJ0, F6NHD9, Q4VBS8
      Related
      ENSDARP00000062174.4, ENSDART00000062175.7
      Conserved Domains (1) summary
      pfam04511
      Location:13 → 203
      DER1; Der1-like family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      58997213..59009175
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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