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    ppip5k1a diphosphoinositol pentakisphosphate kinase 1a [ Danio rerio (zebrafish) ]

    Gene ID: 556748, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ppip5k1aprovided by ZNC
    Official Full Name
    diphosphoinositol pentakisphosphate kinase 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100426-4
    See related
    Ensembl:ENSDARG00000076143 AllianceGenome:ZFIN:ZDB-GENE-100426-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ppip5k1
    Summary
    Predicted to enable 5-diphosphoinositol pentakisphosphate 1-kinase activity; ATP binding activity; and inositol hexakisphosphate kinase activity. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytosol and plasma membrane. Orthologous to human PPIP5K1 (diphosphoinositol pentakisphosphate kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ppip5k1a in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (52761826..52821984)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (52486765..52547698)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 280D Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene microtubule-associated protein 1Aa Neighboring gene tumor protein p53 binding protein, 1 Neighboring gene tubulin gamma complex component 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Integrated transcriptome and phosphoproteome analyses reveal that fads2 is critical for maintaining body LC-PUFA homeostasis. Zhao Y, et al. J Proteomics, 2020 Oct 30. PMID 32891890
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables diphosphoinositol pentakisphosphate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol hexakisphosphate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
    Names
    diphosphoinositol pentakisphosphate kinase 1
    XP_009301735.1
    XP_021333641.1
    XP_021333642.1
    XP_021333643.1
    XP_021333644.1
    XP_021333645.1
    XP_068078831.1
    XP_684718.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      52761826..52821984
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068222730.1 → XP_068078831.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1

    2. XM_009303460.4 → XP_009301735.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X5

      UniProtKB/TrEMBL
      A0A8M3B4E4, E7FFN5
      Related
      ENSDARP00000097715.2, ENSDART00000111444.5
      Conserved Domains (1) summary
      pfam00328
      Location:391 → 906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    3. XM_021477966.2 → XP_021333641.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9QD12
      Conserved Domains (1) summary
      pfam00328
      Location:391 → 906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    4. XM_021477967.2 → XP_021333642.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PQ41
      Conserved Domains (1) summary
      pfam00328
      Location:391 → 906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    5. XM_679626.9 → XP_684718.4  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X7

      UniProtKB/TrEMBL
      A0A8N7UVM3
      Conserved Domains (1) summary
      pfam00328
      Location:391 → 906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    6. XM_021477968.2 → XP_021333643.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8M9Q2S4
      Conserved Domains (1) summary
      pfam00328
      Location:391 → 906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    7. XM_021477969.2 → XP_021333644.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X6

      UniProtKB/TrEMBL
      A0A8M9Q8X0
      Conserved Domains (1) summary
      pfam00328
      Location:391 → 906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)

    8. XM_021477970.2 → XP_021333645.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X8

      UniProtKB/TrEMBL
      A0A8M9QI11
      Conserved Domains (1) summary
      pfam00328
      Location:391 → 906
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    Nucleotide Protein Strain
    Heading Accession and Version

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