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    smtnb smoothelin b [ Danio rerio (zebrafish) ]

    Gene ID: 664685, updated on 9-Dec-2024

    Summary

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    Official Symbol
    smtnbprovided by ZNC
    Official Full Name
    smoothelin bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070912-2
    See related
    AllianceGenome:ZFIN:ZDB-GENE-070912-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    smtn
    Summary
    Is expressed in gut and swim bladder. Orthologous to human SMTN (smoothelin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See smtnb in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (69291732..69413772, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (68520618..68642178, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene inositol polyphosphate-5-phosphatase Jb Neighboring gene selenoprotein M Neighboring gene cyclin O Neighboring gene iron-sulfur cluster assembly 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal expression of smooth muscle markers in developing zebrafish gut. Georgijevic S, et al. Dev Dyn, 2007 Jun. PMID 17474123
    2. Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis. Hachimi M, et al. Curr Biol, 2021 Feb 22. PMID 33275893, Free PMC Article
    3. miR-145 directs intestinal maturation in zebrafish. Zeng L, et al. Proc Natl Acad Sci U S A, 2009 Oct 20. PMID 19805048, Free PMC Article
    4. Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions. Gallagher TL, et al. Dev Biol, 2011 Nov 15. PMID 21925157, Free PMC Article
    5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    smoothelin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      69291732..69413772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221576.1 → XP_068077677.1  smoothelin isoform X4

      UniProtKB/TrEMBL
      A0A8M9PLM4

    2. XM_068221575.1 → XP_068077676.1  smoothelin isoform X2

      UniProtKB/TrEMBL
      A0A8M9PLM4

    3. XM_021476693.2 → XP_021332368.1  smoothelin isoform X3

      UniProtKB/TrEMBL
      A0A8M9PZ83, A0A8M9QEZ1
      Conserved Domains (2) summary
      pfam00307
      Location:777 → 885
      CH; Calponin homology (CH) domain
      pfam12510
      Location:553 → 602
      Smoothelin; Smoothelin cytoskeleton protein

    4. XM_021476691.2 → XP_021332366.1  smoothelin isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q9X3, A0A8M9QEZ1
      Conserved Domains (3) summary
      pfam00307
      Location:788 → 896
      CH; Calponin homology (CH) domain
      pfam12510
      Location:553 → 602
      Smoothelin; Smoothelin cytoskeleton protein
      pfam14738
      Location:572 → 651
      PaaSYMP; Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1

    5. XM_068221574.1 → XP_068077675.1  smoothelin isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q9X3, A0A8M9QEZ1
    Nucleotide Protein Strain
    Heading Accession and Version

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