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    eif3ja eukaryotic translation initiation factor 3, subunit Ja [ Danio rerio (zebrafish) ]

    Gene ID: 394189, updated on 9-Dec-2024

    Summary

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    Official Symbol
    eif3japrovided by ZNC
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Japrovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1266
    See related
    Ensembl:ENSDARG00000012603 AllianceGenome:ZFIN:ZDB-GENE-040426-1266
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    eif3j; eif3s1; fb48g07; zgc:63801; wu:fb48g07
    Summary
    Predicted to enable translation initiation factor activity. Predicted to be involved in formation of cytoplasmic translation initiation complex. Predicted to act upstream of or within translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; midbrain; and segmental plate. Orthologous to human EIF3J (eukaryotic translation initiation factor 3 subunit J). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See eif3ja in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (31900825..31907668, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (31489864..31496693, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene poly (ADP-ribose) polymerase family, member 16 Neighboring gene si:ch73-330k17.3 Neighboring gene amyloid beta (A4) precursor protein-binding, family A, member 2a Neighboring gene dual oxidase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC63801

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in formation of cytoplasmic translation initiation complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic 43S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic 48S preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic translation initiation factor 3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of eukaryotic translation initiation factor 3 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of eukaryotic translation initiation factor 3 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 3 subunit J-A
    Names
    eukaryotic translation initiation factor 3, subunit 1 alpha
    eukaryotic translation initiation factor 3, subunit J

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201214.2 → NP_957508.2  eukaryotic translation initiation factor 3 subunit J-A

      Status: VALIDATED

      Source sequence(s)
      CU694372
      UniProtKB/Swiss-Prot
      Q7SXU0
      Related
      ENSDARP00000124801.1, ENSDART00000149471.3
      Conserved Domains (1) summary
      pfam08597
      Location:5 → 249
      eIF3_subunit; Translation initiation factor eIF3 subunit

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      31900825..31907668 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7SXU0.1 GenPept UniProtKB/Swiss-Prot:Q7SXU0

    Gene LinkOut

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