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    taf1a TATA box binding protein (TBP)-associated factor, RNA polymerase I, A [ Danio rerio (zebrafish) ]

    Gene ID: 567105, updated on 9-Dec-2024

    Summary

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    Official Symbol
    taf1aprovided by ZNC
    Official Full Name
    TATA box binding protein (TBP)-associated factor, RNA polymerase I, Aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041014-272
    See related
    Ensembl:ENSDARG00000052471 AllianceGenome:ZFIN:ZDB-GENE-041014-272
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:136232; si:ch211-180b22.3
    Summary
    Acts upstream of or within heart contraction. Predicted to be part of RNA polymerase I transcription regulator complex. Orthologous to human TAF1A (TATA-box binding protein associated factor, RNA polymerase I subunit A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See taf1a in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (51813413..51874287)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (52001532..52062382)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene BRO1 domain and CAAX motif containing Neighboring gene axin interactor, dorsalization associated Neighboring gene MIA SH3 domain ER export factor 3 Neighboring gene dual specificity phosphatase 10 Neighboring gene uncharacterized LOC137488705

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Recessive TAF1A mutations reveal ribosomopathy in siblings with end-stage pediatric dilated cardiomyopathy. Long PA, et al. Hum Mol Genet, 2017 Aug 1. PMID 28472305, Free PMC Article
    2. Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. Aanes H, et al. Genome Res, 2011 Aug. PMID 21555364, Free PMC Article
    3. Expressed sequence tag analysis of expression profiles of zebrafish testis and ovary. Zeng S, et al. Gene, 2002 Jul 10. PMID 12234666
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC136232

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within heart contraction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within transcription by RNA polymerase I IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase I transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TATA box-binding protein-associated factor RNA polymerase I subunit A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045274.1 → NP_001038739.1  TATA box-binding protein-associated factor RNA polymerase I subunit A

      See identical proteins and their annotated locations for NP_001038739.1

      Status: PROVISIONAL

      Source sequence(s)
      BC116466
      UniProtKB/TrEMBL
      Q1JQ67
      Related
      ENSDARP00000068819.4, ENSDART00000074330.5
      Conserved Domains (1) summary
      pfam14929
      Location:54 → 394
      TAF1_subA; TAF RNA Polymerase I subunit A

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      51813413..51874287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160890.5 → XP_005160947.1  TATA box-binding protein-associated factor RNA polymerase I subunit A isoform X1

      UniProtKB/TrEMBL
      A0A8M2B7S7, Q5SP02
      Related
      ENSDARP00000107952.2, ENSDART00000127444.4
      Conserved Domains (1) summary
      pfam14929
      Location:54 → 394
      TAF1_subA; TAF RNA Polymerase I subunit A

    2. XM_068215531.1 → XP_068071632.1  TATA box-binding protein-associated factor RNA polymerase I subunit A isoform X1

      UniProtKB/TrEMBL
      A0A8M2B7S7, Q5SP02
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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