U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mllt1b MLLT1 super elongation complex subunit b [ Danio rerio (zebrafish) ]

    Gene ID: 678639, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mllt1bprovided by ZNC
    Official Full Name
    MLLT1 super elongation complex subunit bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060421-7142
    See related
    Ensembl:ENSDARG00000031709 AllianceGenome:ZFIN:ZDB-GENE-060421-7142
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fj79f01; zgc:136639
    Summary
    Predicted to enable chromatin binding activity and lysine-acetylated histone binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in prechordal plate. Orthologous to human MLLT1 (MLLT1 super elongation complex subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mllt1b in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (22970124..22993624, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (23314469..23338017, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene myosin VIIBb Neighboring gene uncharacterized LOC103910043 Neighboring gene Sin3A-associated protein b Neighboring gene zinc finger protein 414 Neighboring gene MAPK interacting serine/threonine kinase 2a

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis. Farrell JA, et al. Science, 2018 Jun 1. PMID 29700225, Free PMC Article
    2. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Zhang Y, et al. Cell Rep, 2017 Jan 10. PMID 28076796, Free PMC Article
    3. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC136639

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    MLLT1 super elongation complex subunit b
    Names
    myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 b
    myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1b

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040384.1 → NP_001035474.1  MLLT1 super elongation complex subunit b

      See identical proteins and their annotated locations for NP_001035474.1

      Status: PROVISIONAL

      Source sequence(s)
      BC115206
      UniProtKB/TrEMBL
      Q1RM01
      Related
      ENSDARP00000090508.3, ENSDART00000099735.5
      Conserved Domains (1) summary
      pfam03366
      Location:29 → 109
      YEATS; YEATS family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      22970124..22993624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068224918.1 → XP_068081019.1  MLLT1 super elongation complex subunit b isoform X5

    2. XM_009298518.4 → XP_009296793.1  MLLT1 super elongation complex subunit b isoform X4

      UniProtKB/TrEMBL
      A0A8M3B092
      Conserved Domains (1) summary
      pfam03366
      Location:29 → 109
      YEATS; YEATS family

    3. XM_009298517.4 → XP_009296792.1  MLLT1 super elongation complex subunit b isoform X2

      UniProtKB/TrEMBL
      A0A8M3AQ75
      Conserved Domains (1) summary
      pfam03366
      Location:29 → 109
      YEATS; YEATS family

    4. XM_005171213.5 → XP_005171270.1  MLLT1 super elongation complex subunit b isoform X3

      UniProtKB/TrEMBL
      A0A8M2BIX7
      Conserved Domains (1) summary
      pfam03366
      Location:29 → 109
      YEATS; YEATS family

    5. XM_005171212.5 → XP_005171269.1  MLLT1 super elongation complex subunit b isoform X1

      UniProtKB/TrEMBL
      A0A8M2BIJ1
      Conserved Domains (1) summary
      pfam03366
      Location:29 → 109
      YEATS; YEATS family

    6. XM_009298519.4 → XP_009296794.1  MLLT1 super elongation complex subunit b isoform X6

      UniProtKB/TrEMBL
      A0A8M3AX88
      Conserved Domains (1) summary
      pfam03366
      Location:29 → 109
      YEATS; YEATS family
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools