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    ndufs6 NADH:ubiquinone oxidoreductase subunit S6 [ Danio rerio (zebrafish) ]

    Gene ID: 447913, updated on 21-Dec-2024

    Summary

    Official Symbol
    ndufs6provided by ZNC
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit S6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040912-86
    See related
    Ensembl:ENSDARG00000056583 AllianceGenome:ZFIN:ZDB-GENE-040912-86
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:103774
    Summary
    Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in cervical cancer and nuclear type mitochondrial complex I deficiency 9. Orthologous to human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ndufs6 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (28281206..28283873, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (28696983..28699650, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene iroquois homeobox 1b Neighboring gene iroquois homeobox 4b Neighboring gene mitochondrial ribosomal protein L36 Neighboring gene lysophosphatidylcholine acyltransferase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mitochondrial electron transport, NADH to ubiquinone IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) Fe-S protein 6
    NP_001004651.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004651.1NP_001004651.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

      See identical proteins and their annotated locations for NP_001004651.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081528
      UniProtKB/TrEMBL
      Q66I52
      Related
      ENSDARP00000073559.4, ENSDART00000079104.6
      Conserved Domains (1) summary
      pfam10276
      Location:86123
      zf-CHCC; Zinc-finger domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      28281206..28283873 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)