ints3 integrator complex subunit 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ints3provided by ZNC
Official Full Name: integrator complex subunit 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-060503-634
See related: Ensembl:ENSDARG00000016811 AllianceGenome:ZFIN:ZDB-GENE-060503-634
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-27c15.2
Summary: Predicted to be involved in DNA repair; mitotic G2/M transition checkpoint; and response to ionizing radiation. Predicted to act upstream of or within DNA damage response. Predicted to be located in nucleus. Predicted to be part of SOSS complex. Orthologous to human INTS3 (integrator complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (26640097..26673869)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (27055874..27089646)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
involved_in DNA repair	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitotic G2/M transition checkpoint	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to ionizing radiation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of SOSS complex	ISS Inferred from Sequence or Structural Similarity more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: integrator complex subunit 3

Names: SOSS complex subunit A; SOSS-A; int3; sensor of single-strand DNA complex subunit A; sensor of ssDNA subunit A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.