rcvrn2 recoverin 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rcvrn2provided by ZNC
Official Full Name: recoverin 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7590
See related: Ensembl:ENSDARG00000019902 AllianceGenome:ZFIN:ZDB-GENE-030131-7590
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: rcv1; rcv2a; fk53a03; zgc:73121; wu:fk53a03
Summary: Predicted to enable calcium ion binding activity. Acts upstream of or within cone photoresponse recovery. Is expressed in epiphysis; eye; retina; retinal outer nuclear layer; and retinal photoreceptor layer. Orthologous to human RCVRN (recoverin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 16

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (13911692..13921415, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (14021572..14031295, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fk53a03.x1 (e-PCR)
- UniSTS:201132

fc41d01.x1 (e-PCR)
- UniSTS:193774

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables calcium ion binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cone photoresponse recovery	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within cone photoresponse recovery	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of signal transduction	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: recoverin 2

Names: recoverin-2a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199964.1 → NP_956258.1 recoverin 2

See identical proteins and their annotated locations for NP_956258.1

Status: PROVISIONAL

Source sequence(s)

BC059485

UniProtKB/TrEMBL

A0A0K2CJH9, F6P0K4, Q6PC38

Related

ENSDARP00000011506.7, ENSDART00000023543.9

Conserved Domains (3) summary

COG5126
Location:14 → 181

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

cd00051
Location:65 → 125

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam13833
Location:40 → 87

EF-hand_8; EF-hand domain pair