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    zp3c zona pellucida glycoprotein 3c [ Danio rerio (zebrafish) ]

    Gene ID: 563179, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zp3cprovided by ZNC
    Official Full Name
    zona pellucida glycoprotein 3cprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060817-5
    See related
    Ensembl:ENSDARG00000092919 AllianceGenome:ZFIN:ZDB-GENE-060817-5
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zpc4b
    Summary
    Predicted to enable acrosin binding activity. Predicted to be involved in binding activity of sperm to zona pellucida; egg coat formation; and positive regulation of acrosome reaction. Predicted to be active in extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See zp3c in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (49514224..49521407, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (48869804..48876987, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene calcium homeostasis modulator 1b Neighboring gene inositol 1,4,5-trisphosphate receptor-interacting protein Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 56.4 Neighboring gene HECT and RLD domain containing E3 ubiquitin protein ligase 56.3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Tandem-repeated Zebrafish zp3 genes possess oocyte-specific promoters and are insensitive to estrogen induction. Liu X, et al. Biol Reprod, 2006 Jun. PMID 16481590
    2. Bioinformatic analyses of zona pellucida genes in vertebrates and their expression in Nile tilapia. Wu T, et al. Fish Physiol Biochem, 2018 Apr. PMID 29307115
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uncharacterized protein LOC563179
    Names
    zp3v1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001327992.1 → NP_001314921.1  uncharacterized protein LOC563179 isoform a precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (a).
      Source sequence(s)
      BX321880, CR812943, EH555649, EH576753
      UniProtKB/TrEMBL
      A0A8M1P8M5
      Related
      ENSDARP00000123019.1, ENSDART00000143474.2
      Conserved Domains (2) summary
      smart00241
      Location:122 → 372
      ZP; Zona pellucida (ZP) domain
      pfam00100
      Location:247 → 371
      Zona_pellucida; Zona pellucida-like domain

    2. NM_001327993.1 → NP_001314922.1  uncharacterized protein LOC563179 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 5' terminal exon and it thus differs in its 5' UTR and initiates translation from an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
      Source sequence(s)
      BX321880, CR812943, EH555649, EH576753
      UniProtKB/TrEMBL
      A0A2R8RMU0, A0A8M1P456
      Related
      ENSDARP00000148867.1, ENSDART00000189845.1
      Conserved Domains (1) summary
      pfam00100
      Location:91 → 215
      Zona_pellucida; Zona pellucida-like domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      49514224..49521407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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