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    mpp1 MAGUK p55 scaffold protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 325542, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mpp1provided by ZNC
    Official Full Name
    MAGUK p55 scaffold protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031113-4
    See related
    Ensembl:ENSDARG00000105287 AllianceGenome:ZFIN:ZDB-GENE-031113-4
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb997; zgc:77039; wu:fc85f03
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be located in membrane. Predicted to be active in cell-cell junction and plasma membrane. Is expressed in macrophage; pancreas primordium; pancreatic bud; ventral mesenchyme; and yolk syncytial layer. Orthologous to human MPP1 (MAGUK p55 scaffold protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See mpp1 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (37688487..37733338, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (36291732..36338673, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101885280 Neighboring gene uncharacterized LOC110438244 Neighboring gene G protein-coupled receptor 34 like Neighboring gene uncharacterized LOC110438245 Neighboring gene gamma-aminobutyric acid type A receptor subunit beta4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Drosophila Varicose, a member of a new subgroup of basolateral MAGUKs, is required for septate junctions and tracheal morphogenesis. Wu VM, et al. Development, 2007 Mar. PMID 17267446, Free PMC Article
    2. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery. Tiefenbach J, et al. PLoS One, 2010 Mar 22. PMID 20339547, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell-cell junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    55 kDa erythrocyte membrane protein
    Names
    membrane palmitoylated protein 1
    membrane protein, palmitoylated 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214692.2 → NP_999857.2  55 kDa erythrocyte membrane protein

      Status: VALIDATED

      Source sequence(s)
      CR932985
      UniProtKB/TrEMBL
      Q6NWY1
      Related
      ENSDARP00000131512.1, ENSDART00000157826.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      37688487..37733338 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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