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    si:ch73-299h12.6 si:ch73-299h12.6 [ Danio rerio (zebrafish) ]

    Gene ID: 100150691, updated on 9-Dec-2024

    Summary

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    Official Symbol
    si:ch73-299h12.6provided by ZNC
    Official Full Name
    si:ch73-299h12.6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081031-44
    See related
    Ensembl:ENSDARG00000101319 AllianceGenome:ZFIN:ZDB-GENE-081031-44
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:rp71-1h20.2; si:rp71-1h20.3; si:rp71-1h20.4
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Orthologous to human ZNF572 (zinc finger protein 572). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See si:ch73-299h12.6 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (2289256..2299028, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (2263432..2273272, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene BMP-inhibitory-factor 1.2 Neighboring gene si:ch73-299h12.4 Neighboring gene si:ch211-241b2.1 Neighboring gene zgc:66483

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of immune system process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100150691

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001144820.2 → NP_001138292.1  uncharacterized protein LOC100150691

      See identical proteins and their annotated locations for NP_001138292.1

      Status: VALIDATED

      Source sequence(s)
      EH548266, EH594247
      UniProtKB/TrEMBL
      A0A0R4IDJ9, A0A8M2B7W3
      Related
      ENSDARP00000132169.1, ENSDART00000168712.2
      Conserved Domains (4) summary
      COG5048
      Location:24 → 198
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:159 → 179
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:185 → 207
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:199 → 222
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      2289256..2299028 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005160934.5 → XP_005160991.1  uncharacterized protein LOC100150691 isoform X1

      See identical proteins and their annotated locations for XP_005160991.1

      UniProtKB/TrEMBL
      A0A0R4IDJ9, A0A8M2B7W3
      Conserved Domains (4) summary
      COG5048
      Location:24 → 198
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:159 → 179
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:185 → 207
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:199 → 222
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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