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    cdc23 CDC23 (cell division cycle 23, yeast, homolog) [ Danio rerio (zebrafish) ]

    Gene ID: 393907, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cdc23provided by ZNC
    Official Full Name
    CDC23 (cell division cycle 23, yeast, homolog)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-866
    See related
    Ensembl:ENSDARG00000044484 AllianceGenome:ZFIN:ZDB-GENE-040426-866
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56013
    Summary
    Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein ubiquitination. Predicted to be part of anaphase-promoting complex. Orthologous to human CDC23 (cell division cycle 23). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See cdc23 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (34849423..34879272)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (34814933..34844782)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene WD repeat domain 55 Neighboring gene zgc:56585 Neighboring gene kinesin family member 20A Neighboring gene si:dkey-71d15.2 Neighboring gene lipase, member Ia

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC56013

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell division IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of mitotic metaphase/anaphase transition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of anaphase-promoting complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cell division cycle protein 23 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200933.1 → NP_957227.1  cell division cycle protein 23 homolog

      See identical proteins and their annotated locations for NP_957227.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045861
      UniProtKB/TrEMBL
      A9JTC3, F6P0T3, Q7ZVH3
      Related
      ENSDARP00000065324.4, ENSDART00000065325.5
      Conserved Domains (4) summary
      sd00006
      Location:314 → 342
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:350 → 381
      TPR_1; Tetratricopeptide repeat
      pfam04049
      Location:11 → 137
      ANAPC8; Anaphase promoting complex subunit 8 / Cdc23
      pfam13414
      Location:350 → 413
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      34849423..34879272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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