slc25a37 solute carrier family 25 member 37 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc25a37provided by ZNC
Official Full Name: solute carrier family 25 member 37provided by ZNC
Primary source: ZFIN:ZDB-GENE-031118-202
See related: Ensembl:ENSDARG00000073743 AllianceGenome:ZFIN:ZDB-GENE-031118-202
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: frs; mfrn; mfrn1; fc73c03; wu:fc73c03
Summary: Enables iron ion transmembrane transporter activity. Acts upstream of or within embryonic hemopoiesis; erythrocyte maturation; and iron import into the mitochondrion. Located in mitochondrion. Is expressed in hematopoietic system; kidney; and lateral plate mesoderm. Orthologous to human SLC25A37 (solute carrier family 25 member 37). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (50190678..50220317)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (50202124..50231671)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc73c03.x1 (e-PCR)
- UniSTS:194388

fc73c08.x1 (e-PCR)
- UniSTS:194390

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ferrous iron transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables iron ion transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryonic hemopoiesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within erythrocyte development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within erythrocyte maturation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in iron import into the mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within iron import into the mitochondrion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within iron ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitoferrin-1

Names: erythroid-specific mitochondrial mitoferrin; frascati; mfrn 1; mitochondrial iron transporter 1; mitoferrin; protein frascati; solute carrier family 25 (mitochondrial iron transporter), member 37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.