pabpc1b poly A binding protein, cytoplasmic 1 b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pabpc1bprovided by ZNC
Official Full Name: poly A binding protein, cytoplasmic 1 bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050308-1
See related: Ensembl:ENSDARG00000021140 AllianceGenome:ZFIN:ZDB-GENE-050308-1
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: pabpc1; zgc:77608
Summary: Predicted to enable RNA binding activity. Predicted to act upstream of or within mRNA processing. Predicted to be located in cytoplasm. Is expressed in several structures, including alar plate midbrain region; nervous system; notochord; pronephric duct; and yolk syncytial layer. Orthologous to several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (12121944..12145730, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (12202416..12226202, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: polyadenylate-binding protein 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200882.1 → NP_957176.1 polyadenylate-binding protein 1b

See identical proteins and their annotated locations for NP_957176.1

Status: PROVISIONAL

Source sequence(s)

BC063948

UniProtKB/TrEMBL

Q6P3L1, Q6PBL8

Related

ENSDARP00000034822.9, ENSDART00000032474.11

Conserved Domains (6) summary

TIGR01628
Location:11 → 613

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

cd12378
Location:12 → 91

RRM1_I_PABPs; RNA recognition motif 1 in type I polyadenylate-binding proteins

cd12379
Location:97 → 172

RRM2_I_PABPs; RNA recognition motif 2 found in type I polyadenylate-binding proteins

cd12380
Location:190 → 269

RRM3_I_PABPs; RNA recognition motif 3 found in type I polyadenylate-binding proteins

cd12381
Location:293 → 370

RRM4_I_PABPs; RNA recognition motif 4 in type I polyadenylate-binding proteins

pfam00658
Location:545 → 612

PABP; Poly-adenylate binding protein, unique domain