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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_080867.3 → NP_543143.1 suppressor of cytokine signaling 4
See identical proteins and their annotated locations for NP_543143.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an exon in the 5' region, as compared to variant 1.
- Source sequence(s)
-
AK126195, BC060790, BX161418, BX648734
- Consensus CDS
-
CCDS9722.1
- UniProtKB/Swiss-Prot
-
Q8WXH5
- UniProtKB/TrEMBL
- B3KW39, Q5H9R6
- Related
- ENSP00000378855.2, ENST00000395472.2
- Conserved Domains (3) summary
-
- cd10385
Location:275 → 375
- SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
- cd03738
Location:384 → 439
- SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
- pfam12610
Location:59 → 111
- SOCS; Suppressor of cytokine signalling
-
NM_199421.2 → NP_955453.1 suppressor of cytokine signaling 4
See identical proteins and their annotated locations for NP_955453.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) is the longer transcript and it has an additional exon in the 5' region.
- Source sequence(s)
-
AK126195, BC060790, BX648734, CD109883
- Consensus CDS
-
CCDS9722.1
- UniProtKB/Swiss-Prot
-
Q8WXH5
- UniProtKB/TrEMBL
- B3KW39, Q5H9R6
- Related
- ENSP00000452522.1, ENST00000555846.2
- Conserved Domains (3) summary
-
- cd10385
Location:275 → 375
- SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
- cd03738
Location:384 → 439
- SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
- pfam12610
Location:59 → 111
- SOCS; Suppressor of cytokine signalling
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000014.9 Reference GRCh38.p14 Primary Assembly
- Range
-
55027236..55049489
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011536425.2 → XP_011534727.1 suppressor of cytokine signaling 4 isoform X1
See identical proteins and their annotated locations for XP_011534727.1
- UniProtKB/Swiss-Prot
-
Q8WXH5
- UniProtKB/TrEMBL
- B3KW39, Q5H9R6
- Conserved Domains (3) summary
-
- cd10385
Location:275 → 375
- SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
- cd03738
Location:384 → 439
- SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
- pfam12610
Location:59 → 111
- SOCS; Suppressor of cytokine signalling
-
XM_011536426.2 → XP_011534728.1 suppressor of cytokine signaling 4 isoform X1
See identical proteins and their annotated locations for XP_011534728.1
- UniProtKB/Swiss-Prot
-
Q8WXH5
- UniProtKB/TrEMBL
- B3KW39, Q5H9R6
- Conserved Domains (3) summary
-
- cd10385
Location:275 → 375
- SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
- cd03738
Location:384 → 439
- SOCS_SOCS4; SOCS (suppressors of cytokine signaling) box of SOCS4-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
- pfam12610
Location:59 → 111
- SOCS; Suppressor of cytokine signalling
Alternate T2T-CHM13v2.0
Genomic
-
NC_060938.1 Alternate T2T-CHM13v2.0
- Range
-
49232425..49254678
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054375392.1 → XP_054231367.1 suppressor of cytokine signaling 4 isoform X1
- UniProtKB/Swiss-Prot
-
Q8WXH5
- UniProtKB/TrEMBL
- B3KW39, Q5H9R6
-
XM_054375393.1 → XP_054231368.1 suppressor of cytokine signaling 4 isoform X1
- UniProtKB/Swiss-Prot
-
Q8WXH5
- UniProtKB/TrEMBL
- B3KW39, Q5H9R6