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    Slc25a53 solute carrier family 25, member 53 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679135, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc25a53provided by RGD
    Official Full Name
    solute carrier family 25, member 53provided by RGD
    Primary source
    RGD:1591860
    See related
    EnsemblRapid:ENSRNOG00000069699 AllianceGenome:RGD:1591860
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mcart1l
    Summary
    Predicted to be located in membrane and mitochondrion. Orthologous to human SLC25A53 (solute carrier family 25 member 53). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 24.5), Spleen (RPKM 20.4) and 4 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc25a53 in Genome Data Viewer
    Location:
    Xq32
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (105099191..105111936, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (100306917..100319662, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (107622504..107632594, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene H2B.W histone 2 like Neighboring gene thymosin beta 15B2 Neighboring gene zinc finger, CCHC domain containing 18 Neighboring gene vacuolar ATPase assembly factor VMA21, pseudogene 1 Neighboring gene uncharacterized LOC108349241

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC187490

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables NAD transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier family 25 member 53
    Names
    mitochondrial carrier triple repeat 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127602.2 → NP_001121074.1  solute carrier family 25 member 53

      See identical proteins and their annotated locations for NP_001121074.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6KNU8, B2GUW8
      Related
      ENSRNOP00000106733.1, ENSRNOT00000148829.1
      Conserved Domains (1) summary
      pfam00153
      Location:110 → 203
      Mito_carr; Mitochondrial carrier protein

    2. NM_001419570.1 → NP_001406499.1  solute carrier family 25 member 53

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6KNU8, B2GUW8
      Related
      ENSRNOP00000095987.1, ENSRNOT00000094538.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      105099191..105111936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100049.1 → XP_038955977.1  solute carrier family 25 member 53 isoform X1

      UniProtKB/TrEMBL
      A6KNU8, B2GUW8
      Related
      ENSRNOP00000092509.1, ENSRNOT00000093992.2
      Conserved Domains (1) summary
      pfam00153
      Location:110 → 203
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein Strain
    Heading Accession and Version

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