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    Or5h17 olfactory receptor family 5 subfamily H member 17 [ Mus musculus (house mouse) ]

    Gene ID: 258478, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Or5h17provided by MGI
    Official Full Name
    olfactory receptor family 5 subfamily H member 17provided by MGI
    Primary source
    MGI:MGI:3030017
    See related
    Ensembl:ENSMUSG00000062105 AllianceGenome:MGI:3030017
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr183; MOR183-2
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or5h17 in Genome Data Viewer
    Location:
    16 C1.2- C1.3; 16 34.83 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (58749781..58820979)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (58929418..59000616)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily K member 16 Neighboring gene olfactory receptor family 5 subfamily K member 17 Neighboring gene olfactory receptor family 5 subfamily AB member 1, pseudogene 1 Neighboring gene olfactory receptor 184, pseudogene 1 Neighboring gene olfactory receptor family 5 subfamily AD member 1, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Michaloski JS, et al. Genome Res, 2006 Sep. PMID 16902085, Free PMC Article
    2. Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures. de March CA, et al. Mol Cell Neurosci, 2020 Apr. PMID 32061665, Free PMC Article
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This odorant receptor, Olfr183, responds to the odorant isoamyl acetate in both in vivo and in vitro assays
      Title: Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 5H17
    Names
    GA_x54KRFPKG5P-55229158-55230087
    olfactory receptor 183
    olfactory receptor 183-2
    olfactory receptor MOR183-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146485.2 → NP_666696.2  olfactory receptor 5H17

      Status: VALIDATED

      Source sequence(s)
      AC154545, DR065568, DR065627
      Consensus CDS
      CCDS28241.1
      UniProtKB/Swiss-Prot
      Q8VFB9
      UniProtKB/TrEMBL
      A0A0U1RNJ0, E9QKE8
      Related
      ENSMUSP00000080602.3, ENSMUST00000073320.5
      Conserved Domains (2) summary
      cd14964
      Location:27 → 51
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:25 → 303
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      58749781..58820979
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017316985.1 → XP_017172474.1  olfactory receptor 5H17 isoform X1

      UniProtKB/Swiss-Prot
      Q8VFB9
      UniProtKB/TrEMBL
      A0A0U1RNJ0, E9QKE8
      Conserved Domains (2) summary
      cd14964
      Location:27 → 51
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:25 → 303
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VFB9.1 GenPept UniProtKB/Swiss-Prot:Q8VFB9

    Gene LinkOut

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