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    Arxes2 adipocyte-related X-chromosome expressed sequence 2 [ Mus musculus (house mouse) ]

    Gene ID: 76976, updated on 9-Dec-2024

    Summary

    Official Symbol
    Arxes2provided by MGI
    Official Full Name
    adipocyte-related X-chromosome expressed sequence 2provided by MGI
    Primary source
    MGI:MGI:1924226
    See related
    Ensembl:ENSMUSG00000048040 AllianceGenome:MGI:1924226
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spcs3; Spc22/23; 2900062L11Rik
    Summary
    Acts upstream of or within fat cell differentiation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Arxes2 in Genome Data Viewer
    Location:
    X F1; X 57.35 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (134894569..134896108)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (135993820..135995359)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor associated sorting protein 2 Neighboring gene basic helix-loop-helix domain containing, class B9 Neighboring gene STARR-seq mESC enhancer starr_47972 Neighboring gene predicted gene, 31214 Neighboring gene adipocyte-related X-chromosome expressed sequence 1 Neighboring gene predicted gene, 54084

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein targeting to ER IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal peptide processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal peptide processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of signal peptidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of signal peptidase complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    adipocyte-related X-chromosome expressed sequence 2
    Names
    SPase 22 kDa subunit
    SPase 22/23 kDa subunit
    microsomal signal peptidase 22/23 kDa subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029823.2NP_084099.1  adipocyte-related X-chromosome expressed sequence 2

      See identical proteins and their annotated locations for NP_084099.1

      Status: VALIDATED

      Source sequence(s)
      AA286632, AK077432, AV333270, BY773138
      Consensus CDS
      CCDS30411.1
      UniProtKB/Swiss-Prot
      B1AUR7, C0HK79, C0HK80, Q8BK31, Q9D365, Q9D6F2
      Related
      ENSMUSP00000051250.8, ENSMUST00000058119.9
      Conserved Domains (1) summary
      pfam04573
      Location:4173
      SPC22; Signal peptidase subunit

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      134894569..134896108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_003642.1: Suppressed sequence

      Description
      NR_003642.1: This RefSeq was permanently suppressed because it is now thought that this gene encodes a protein.