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    Hoxc13 homeobox C13 [ Mus musculus (house mouse) ]

    Gene ID: 15422, updated on 27-Nov-2024

    Summary

    Official Symbol
    Hoxc13provided by MGI
    Official Full Name
    homeobox C13provided by MGI
    Primary source
    MGI:MGI:99560
    See related
    Ensembl:ENSMUSG00000001655 AllianceGenome:MGI:99560
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    N
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and chromatin binding activity. Acts upstream of or within several processes, including hair follicle development; nail development; and tongue morphogenesis. Located in nucleus. Is expressed in several structures, including integumental system; limb; spinal cord; tail; and tongue. Human ortholog(s) of this gene implicated in ectodermal dysplasia 9. Orthologous to human HOXC13 (homeobox C13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Hoxc13 in Genome Data Viewer
    Location:
    15 F3; 15
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (102829566..102837249)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102921131..102928814)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7424 Neighboring gene predicted gene, 36510 Neighboring gene predicted gene, 36560 Neighboring gene chondrogenesis associated transcript Neighboring gene STARR-seq mESC enhancer starr_39859 Neighboring gene homeobox C12 Neighboring gene HOX transcript antisense RNA (non-protein coding)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    homeobox protein Hox-C13
    Names
    naked

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010464.2NP_034594.1  homeobox protein Hox-C13

      See identical proteins and their annotated locations for NP_034594.1

      Status: VALIDATED

      Source sequence(s)
      AC160979
      Consensus CDS
      CCDS27890.1
      UniProtKB/Swiss-Prot
      P50207, Q53Z78, Q920I7
      Related
      ENSMUSP00000001700.7, ENSMUST00000001700.7
      Conserved Domains (2) summary
      pfam00046
      Location:261310
      Homeobox; Homeobox domain
      pfam12284
      Location:52164
      HoxA13_N; Hox protein A13 N terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      102829566..102837249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)