Ptov1 PTOV1, extended AT-hook containing adaptor protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ptov1provided by RGD
Official Full Name: PTOV1, extended AT-hook containing adaptor proteinprovided by RGD
Primary source: RGD:1306977
See related: EnsemblRapid:ENSRNOG00000020358 AllianceGenome:RGD:1306977
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of transcription regulator complex. Orthologous to human PTOV1 (PTOV1 extended AT-hook containing adaptor protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Muscle (RPKM 219.2), Adrenal (RPKM 203.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q22

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (104483553..104496161, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (95347065..95354514, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (100859346..100866917, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BI290136 (e-PCR)
- UniSTS:243977

RH128246 (e-PCR)
- UniSTS:211554

AU041779 (e-PCR)
- UniSTS:159635

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
part_of transcription regulator complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: prostate tumor-overexpressed gene 1 protein homolog

Names: prostate tumor over expressed gene 1; prostate tumor overexpressed 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008304.1 → NP_001008305.1 prostate tumor-overexpressed gene 1 protein homolog

See identical proteins and their annotated locations for NP_001008305.1

Status: PROVISIONAL

Source sequence(s)

BC085836

UniProtKB/Swiss-Prot

Q5U2W6

UniProtKB/TrEMBL

A6JAT8

Related

ENSRNOP00000027580.3, ENSRNOT00000027580.6

Conserved Domains (1) summary

pfam11232
Location:93 → 238

Med25; Mediator complex subunit 25 PTOV activation and synapsin 2