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    Prelid2 PRELI domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681037, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Prelid2provided by RGD
    Official Full Name
    PRELI domain containing 2provided by RGD
    Primary source
    RGD:1584707
    See related
    EnsemblRapid:ENSRNOG00000067168 AllianceGenome:RGD:1584707
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in mitochondrial intermembrane space. Orthologous to human PRELID2 (PRELI domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 65.0), Heart (RPKM 21.3) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Prelid2 in Genome Data Viewer
    Location:
    18p11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (34120989..34212699, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (33869934..33961320, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (36198522..36286217, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene transketolase, pseudogene 1 Neighboring gene 40S ribosomal protein S28 pseudogene Neighboring gene cyclin-dependent kinase 1 pseudogene Neighboring gene glutaredoxin and cysteine rich domain containing 2 Neighboring gene chaperonin containing Tcp1, subunit 6A (zeta 1), pseudogene 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatidic acid transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in phospholipid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PRELI domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271333.1 → NP_001258262.1  PRELI domain-containing protein 2

      See identical proteins and their annotated locations for NP_001258262.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A0A8I6A2K3, A6J3J3
      Related
      ENSRNOP00000084747.2, ENSRNOT00000096234.2
      Conserved Domains (1) summary
      pfam04707
      Location:16 → 173
      PRELI; PRELI-like family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      34120989..34212699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277588.1 → XP_063133658.1  PRELI domain-containing protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A2K3

    2. XM_039097122.1 → XP_038953050.1  PRELI domain-containing protein 2 isoform X2

      Conserved Domains (1) summary
      pfam04707
      Location:31 → 129
      PRELI; PRELI-like family

    3. XM_008772173.3 → XP_008770395.2  PRELI domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AP10
      Conserved Domains (1) summary
      pfam04707
      Location:1 → 144
      PRELI; PRELI-like family

    4. XM_039097123.2 → XP_038953051.1  PRELI domain-containing protein 2 isoform X3

      Conserved Domains (1) summary
      pfam04707
      Location:16 → 123
      PRELI; PRELI-like family

    RNA

    1. XR_010059597.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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